Gene information
Official symbol SIRT6
Official full name sirtuin 6
Gene type protein-coding gene
Chromosome19p13.3
Gene familySirtuins
Resources
Entrez Gene 51548
HGNC HGNC:14934
Ensembl ENSG00000077463
Vega OTTHUMG00000181847
UCSC uc002lzo.4
GO terms: 59 records
GO Description Category LogP Number of genes Detail
GO:0001936 regulation of endothelial cell proliferation GO Biological Processes -54.5504306 75 More
GO:0001938 positive regulation of endothelial cell proliferation GO Biological Processes -32.0012114 45 More
GO:0006109 regulation of carbohydrate metabolic process GO Biological Processes -13.1742479 35 More
GO:0006140 regulation of nucleotide metabolic process GO Biological Processes -7.41911571 18 More
GO:0006284 base-excision repair GO Biological Processes -1.89871863 3 More
GO:0006974 cellular response to DNA damage stimulus GO Biological Processes -1.56334957 15 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0009895 negative regulation of catabolic process GO Biological Processes -10.3621088 43 More
GO:0009896 positive regulation of catabolic process GO Biological Processes -13.5088608 63 More
GO:0010563 negative regulation of phosphorus metabolic process GO Biological Processes -21.7837721 71 More
GO:0010638 positive regulation of organelle organization GO Biological Processes -6.49207636 47 More
GO:0010675 regulation of cellular carbohydrate metabolic process GO Biological Processes -9.60411715 27 More
GO:0010677 negative regulation of cellular carbohydrate metabolic process GO Biological Processes -4.04738042 9 More
GO:0010827 regulation of glucose transmembrane transport GO Biological Processes -18.4601079 28 More
GO:0010829 negative regulation of glucose transmembrane transport GO Biological Processes -8.17037988 10 More
GO:0016570 histone modification GO Biological Processes -1.66018959 10 More
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO Molecular Functions -7.39079179 12 More
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO Molecular Functions -6.05306731 14 More
GO:0030162 regulation of proteolysis GO Biological Processes -41.2267045 73 More
GO:0031331 positive regulation of cellular catabolic process GO Biological Processes -13.5134767 30 More
GO:0031507 heterochromatin assembly GO Biological Processes -2.56813882 4 More
GO:0031648 protein destabilization GO Biological Processes -1.87243811 6 More
GO:0033500 carbohydrate homeostasis GO Biological Processes -23.7918768 50 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034763 negative regulation of transmembrane transport GO Biological Processes -22.14661 42 More
GO:0042176 regulation of protein catabolic process GO Biological Processes -8.45353494 23 More
GO:0042326 negative regulation of phosphorylation GO Biological Processes -20.6187298 64 More
GO:0042593 glucose homeostasis GO Biological Processes -23.8963802 50 More
GO:0043467 regulation of generation of precursor metabolites and energy GO Biological Processes -10.8295915 27 More
GO:0043470 regulation of carbohydrate catabolic process GO Biological Processes -8.06132628 15 More
GO:0045732 positive regulation of protein catabolic process GO Biological Processes -6.83749864 15 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0045766 positive regulation of angiogenesis GO Biological Processes -39.3444092 63 More
GO:0045814 negative regulation of gene expression, epigenetic GO Biological Processes -2.19985109 4 More
GO:0045862 positive regulation of proteolysis GO Biological Processes -17.3242033 33 More
GO:0045912 negative regulation of carbohydrate metabolic process GO Biological Processes -5.15495164 11 More
GO:0045936 negative regulation of phosphate metabolic process GO Biological Processes -21.8424865 71 More
GO:0046324 regulation of glucose import GO Biological Processes -14.8736114 22 More
GO:0046325 negative regulation of glucose import GO Biological Processes -8.14754197 9 More
GO:0048145 regulation of fibroblast proliferation GO Biological Processes -11.1167439 21 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050679 positive regulation of epithelial cell proliferation GO Biological Processes -31.4834672 59 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051052 regulation of DNA metabolic process GO Biological Processes -4.01973325 42 More
GO:0062012 regulation of small molecule metabolic process GO Biological Processes -26.8746473 69 More
GO:0062014 negative regulation of small molecule metabolic process GO Biological Processes -11.3582124 24 More
GO:0070828 heterochromatin organization GO Biological Processes -3.17098953 5 More
GO:0072091 regulation of stem cell proliferation GO Biological Processes -6.89052200 13 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0120161 regulation of cold-induced thermogenesis GO Biological Processes -19.1025541 38 More
GO:0120162 positive regulation of cold-induced thermogenesis GO Biological Processes -19.5569802 32 More
GO:1900542 regulation of purine nucleotide metabolic process GO Biological Processes -7.57719972 18 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1903578 regulation of ATP metabolic process GO Biological Processes -8.20286273 19 More
GO:1903579 negative regulation of ATP metabolic process GO Biological Processes -4.61361828 8 More
GO:1904018 positive regulation of vasculature development GO Biological Processes -39.3444092 63 More
GO:1905330 regulation of morphogenesis of an epithelium GO Biological Processes -7.22524154 15 More
GO:1905564 positive regulation of vascular endothelial cell proliferation GO Biological Processes -12.8410298 14 More
GO:2001020 regulation of response to DNA damage stimulus GO Biological Processes -1.68933987 9 More
Related studies: 4 records
Molecular factor Omics type Application Objective MI type Reference
NAD-dependent protein deacetylase sirtuin-6 proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Zi Y et al. Cell Death Discov. 2019
NAD-dependent protein deacetylase sirtuin-6 proteomics death[prognosis (bad)] acute myocardial infarction Zi Y et al. Cell Death Discov. 2019
NG_047153.1:g.3915T>C genomics myocardial infarction[diagnosis] myocardial infarction Wang L et al. Genet Test Mol Biomarkers. 2016
NG_047153.1:g.4658C>A genomics myocardial infarction[diagnosis] myocardial infarction Wang L et al. Genet Test Mol Biomarkers. 2016
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